Medical versus surgical treatment for refractory or recurrent peptic ulcer

Treatment of refractory peptic ulcer with omeprazole

Accepted for publication 14 May 1990 Abstract We tested the hypothesis that the gastric H+/K+ adenosine triphosphatase inhibitor, omeprazole, because of its different mode of action and pronounced inhibitory effect on gastric acid secretion, may be more effective in peptic ulcer that is refractory to histamine H2 receptor antagonist treatment than continuing the same therapy. Altogether 107 pat...

The surgical treatment of peptic ulcer.

Medical management of peptic ulcer.

Sir Francis Avery Jones (FAJ-for once the abbreviation means something to everyone) has been actively involved in the practical and research aspects of management of peptic ulcer throughout his long and productive career. Some of FAJ's earliest publications (Avery Jones, 1939a and b, 1943, 1947) deal with management of acute upper alimentary bleeding and he was instrumental in introducing moder...

Surgical treatment of peptic ulcer disease: current indications and techniques

The acute complications of peptic ulcer and their surgical treatment.

It will be seen that three of the cases were under forty and two under forty-five. Except for one case, the length of history was measured in years. Seven of the eight ulcer-cancers occurred in the pyloric antrum, thus confirming that it is the chronic ulcer in this situation which is particularly liable to undergo malignant change. Five of the patients are dead, one was dying when last seen an...